Perinatalnі іnfektsії

Perinatalnі іnfektsії

Mandate of the Ministry of Health of Ukraine ’Health 27.12.2007 № 906
The clinical protocol for obstetric admissions. Perinatalnі іnfektsії
Perinatal Infections I -capture of the fetus aboot
Okremo slіd zachizniti, scho in times of VIL-positive status of mothers and women of the VІL transfer through the breast milk in times of breast vigoduvnya.
Terminiinternal інньутробне інфікування” і “internal інньатробна інфекція"Yea sinonіmami not.


Inside інфікуванняIt is a fact of invasion of microorganism in the body of the fetus, so do not endeavor to produce a pathological development of pathological diseases. The internal understanding of the situation has been significantly reduced, and the community has developed the illnesses and the term is not guilty of vicorisovuvatsya yak diagnostics.


Internal Infusion- the seizure of the fetus, and the diagnosis of hematogenous (transplacental), before the beginning of the problem, but also the infection of the fetus, or by the clinical manifestations of the infection of the people.
To catch the fetus, overwhelm, through the early fetal period (9–22.. Я ов r
   
Mozhvіl nespriyatlі naslіdki perinatal іnfektsіy pіd hour v_v_tnost_:
- zatrimka vіrnіutrobnogo development of the fetus;
- peredchasni pology;
- Vrodzheni wadi rozvitku;
- perinatal vtrati;
- the guests of the infectory in the newly reconciled;
- Persistent infections of the newly reconciled;
- bezsymptomnіinfektsіІ with pіznіmi klinіnymi proyavami;
- інвалідність з дитинства.


Perinatal Infections
1.Depth of passage:
- transplacental;
- vishidny;
- contact;
- Infections, are transmitted through the milk of the mother;
- Infections, are transmitted through products and blood;
- gospііlііinfektsії.
 2.Deposit vid zbudnika:
- bacterial;
- vіrusnі;
- spirokhetno і;
- protozoin;
- zmishans.
Before the fiery inner igneous infecting the confinement, so far from the three final lives (C).
   
Klіnіchnі show the severity of perinatal infections to lie in:
• the type of zbudnika, your first question, the specific features of the problem, the general situation, as well as the fact that it is the primary infection of the person who is chronical;
• Immune homeostasis of the female organism;
• stages of the infecting process at the vagina;
• Termu vaginalness in the Yakom Vidbulsya Informance (Table 1);
• sticking to the penetration of zbudnik in the organ of the vagina.
   
Table 1
Clinical manifestations of intrinsic and perinatal infections
Gestational period                                         Mozhlivі nasledki іnfektsії

Before mantra zygote
(First 6 days after the start)


Embryo-placentogenesis Zagibel embryo, wadi rozvitku, formuvannya placental dysfunction
(from the 7th day to the 8th tizhnya)

Early fetal Porushennya functions of the various organs and systems
(from the 9th to the 22nd day)


Pіznіy fetal Rozvitok fetopatіy abo specificnogo інфекційного process
(after 22 tizhnіv)
The infection of the fetus by singing of the perinatal infectious causes of the development of a similar symptom complex, which was earlier called abrevіaturoyuTORCH,the storage of the first letters of the names of the most part of the internal components:
- T(Toxoplasmosis - Toxoplasmosis);
- o(Other diseases - іnshі - sifіlіs, VІL, Vіtryana vіspa, and also infektsіі, риrynenі enterovіrusami and parvovіrusom B19);
- R(Rubella - rubella);
-C(Cytomegalovirus – cytomegalium);
- H(Herpes simplex virus - herpes).
Signs of perinatal infections:
• malosimptomna clinical picture of the mother;
• symptom complex in the fetus:
- shading growth of the fetus;
- Zhovtyanitsya;
- hepatosplenomegaly;
- Exantemi;
- the central nervous system and organs of the blood circulation;
- Persistent peregіg pain in the newborn;
- access to the general;
ВЂрод vrozhenі wadi rozvitku.
   
   
Methodology diagnostics інфекції під час ваітності
  1.Dosvіdzhenny vm_stu cervical channely, pykhvi, urethra:
- bacterioscope;
- Bacteriological (aka іsne і kіlkіsne);
- вірусологічне.
  2.Doslіdzhenny bloodon the emergence of specific antitiv-serologic doslіdzhennya.
Іnterpretatsіya results_v serologіnyh doslіdzhen
 
1. The appearance in the blood of specific ІgМ-antitіl with the interim igg-antitіl to tell about the early guests of the hostilities.
2. The manifestation of specific anti-illumination of oboh classes related to the public about the inconsistency in the second phase, or about the reactivity of the latent infectious.

When assignedІgМ, ІgG- antitiv pid h vagіnostnі often for various reasons, hibnopositive reactions occur. In this way lice mind zbudnika, termіnu vagіnnosti and іshih obshvein, yakі characterize the situation;
3. The appearance of a igg-anti-ling vagina lisha speak about the camp of the immunity;
4. vіdsutsnіst antitіl oboh klasіv meeting about those, that infeccii in the past is not bullo, but мож potentsialnaya can be the primary іnfіkuvnya pіd hour vіnnostі that viynnenya vnutіrіnnotutno іnк Thus, the repeated serological indications with the method of early discovery, especially for the fetus, are shown.

Table 2
Otsіnka results of serologic doslіzhen s TORCH - agents
ІgМ ІgG Іnterpretatsіya results

+ - Early phase of the hotel infektsi

+ + Gora Infektsia abo zagostrennya chronichno ї
- + Stan інutente pіslya transferred on ін-фекції ї
- - Group riziku (zagroza viknennya Gostoi first privyno ї інфекції):
- seronegative perіod guest of Infektsі
- vіdsutnіst інфекції in the past
 
3.Doslіdzhennya Sichі:
- Bacteriological (aka іsne і kіlkіsne);
- Virusus;
- microscopic;
- biochemical (appointed by nitrit).
Dose of the disease on the method of asymptomatic bacterium ao pid-hardening to the diagnosis of various forms of infectious diseases (urethritis, cystitis, nephritis).
Asymptomatic bacterium is manifested in 1 ml of the middle portions of the microorganism in the kolkost ≥105 (100 000) colonies of oddinitsy (KUO) for each condition of the klіnіhnyh manifestations of manifestations that occur. Mozhlyva tayozh leukocyturia (not obov’yazkovo).
4.Molecular biologic methods:
- ligazna lantsyugova reaction;
- Polimerazna Lantsyugova reaction.
III. Methods of diagnosis of infectious diseases
1.YlithographographyAllow the syndrome of shading growth of the fetus, abnormal number of animals, human, animal, human, animal, plaque, fetal drops, hydrocephalus, cerebral calciphatic, rosacea-mystic system, hepatomegaly, and hepatomegaly;
2.Transabdominal amniocentesis(behind the scenes) for the onslaught of the identification of zudnika in the watered fruit.
3.Cordocentesis(Behind the shows) - the determination of the zudnika / abo rivnya of specific anti-bodies in the umbilical cord.
   
Comprehensively zhenok z me nyu vyyvlennya іnfіkovannostі zbudnikami prenatalnyh infectsіy, especially the group TORCH, slide to the involvement. Lykuvannya tsikh фnfekts_y є one of the main tasks of pregravidno podgotovki. However, it was often part of tsikh infektsіy effectively abo vazalі not lіkuitsya!
Usi zhіnki reproductive vіku, as if planned vagnitt, povnnі buti testovanі na naavnіst antitіl to vіrusu rubella (A). Seronegative zhinkam recommend vaccine with a counter-contraceptive use of drugs. Dotsіlno takozh before nastannya vagіtnostі spend shliplennya against hepatitis B.

Perinatal infections for the main causes of the main reasons for the reasons of the disease, the pathology of the fruit and the newborn. The water tank at the rear end of the billow vipadkiv lіkuvannya pіd hour vagnitnosі not use it abo vono nemaє sensu.
Slam pam'yatati, just to show bacterium in organisms, anti-bodies to infectious agents in the blood of a vagueness means to infecting process.
Gospіtalіzuvaty vagіtnu for lіkuvannya інфекції sіd lisha if take lіkuvannya can not be done on an outpatient basis. In the past Vipadka relocation in the stationary can zashkoditi materі i ditinі.
Do not isolate your country from those who have your country, who have your child, do not make such contact without knowing clearly.
Do not enter the chest through the wounding of the mother of the infestation. Taka vіdmіna vypravdana liche at vipadku VІL - Infektsії that pіd hour of the first perіodu visokontagіozhnogo іnfektsіynyh zakhvoryuvan, they are transmitted by respiratory gate (timchasovo).
Visokiy rіven rozpovsyudzhenostі ІPSSH obumovlyuє neobhіdnіst usіm medichnim pratsіvnikam zavzhdi koristuvatisya zasobami іndivіdualnogo Zahist at kontaktі of bіologіchnimi seredovischami organіzmu vagіtnoї, rodіllі, porodіllі.
Head of Odoron
Zdorovyaya materiv and N.Ya. Vein

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TORCH infection tests are not mandatory and they are not included in the standard examination package for pregnant women. These tests are prescribed according to strict indications in accordance with the clinical protocol “Perinatal infections”, approved by order No. 906 of the Ministry of Health of Ukraine dated December 27, 2006.


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